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App Note: AN4 How to select your best performing single domain antibodies

By May 14, 2024No Comments

A fast, dip-in assay can provide comprehensive kinetic analysis to determine the most appropriate binding proteins

Single domain antibodies (sdAbs) have an improved capacity to penetrate tissues, making them powerful alternatives to conventional antibodies in therapeutics and diagnostics. Although these may prove to be better binders overall, in order to correctly choose the binder suited to your needs, accurate kinetic information must be obtained through screening.

WHITE FOx can provide the crucial kinetic information that is missing from other assays such as ELISA. WHITE FOx’s dip-in sensors can be used to determine the best binder of a biomarker through kinetic analysis of binding to a marker (for example, C-reactive protein).