FOx BIOSYSTEMS flexible applications icon

Fiber-optic surface plasmon resonance (FO-SPR) is a versatile technology that can be adapted for use in a wide variety of additional applications.

The probe has a standard generic coupling chemistry that can be coupled with a range of compounds and used with or without labels. This allows the quantification of proteins, small molecules, DNA or cells in microliter volumes, as well as a wide range of interaction analyses.

Additional probe types are in development and will open up an even broader range of applications.

The fluidics-free setup also eliminates the clogging associated with microfluidics-based alternatives, thereby reducing sample processing steps.

Some of the other exciting things scientists are using our technology for:

  • Biologics production
    • Nanobody- or antibody-antigen kinetic affinity
    • Cellular bioreactor development
    • In-line process control systems
  • DNA / RNA
    • Quantification
    • Hybridization
    • And more
  • Allergen testing in food
    • Peanut
    • Progesterone in dairy milk
  • Potency / denaturation assays
  • Small molecule quantification
  • Fast sandwich assays using gold nanoparticles
  • A wide range of interaction analyses, including potency assays, enzymatic lysis, etc.

The FO-SPR probes can be coupled with a range of compounds. Proteins, antibodies, DNA, small molecules, large particles such as phage, and sandwich assays are all possible using the standard carboxyl chemistry.

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