FOx BIOSYSTEMS flexible applications icon

Fiber-optic surface plasmon resonance (FO-SPR) is a versatile technology that can be adapted for use in a wide variety of additional applications.

Our interchangeable probes are available with four surface chemistries, allowing you to select the most appropriate method for your bioassay.

A generic surface chemistry that serves a wide range of applications
For immobilized His-tag proteins; convenient for nanobodies and recombinant proteins and ideal for display library screening; allows multiplexing
For easy immobilization of biotin-labelled proteins, antibodies or peptides
Protein A
A generic surface for quantifying IgG; ideal for screening IgG libraries for binding potency

This combination of probes allows the quantification of proteins, small molecules, DNA or cells in microliter volumes, as well as a wide range of interaction analyses.

Furthermore, the fluidics-free setup also eliminates the clogging associated with microfluidics-based alternatives, thereby reducing sample processing steps.

Some of the other exciting things scientists are using our technology for:

  • Biologics production
    • Nanobody- or antibody-antigen kinetic affinity
    • Cellular bioreactor development
    • In-line process control systems
    • Analyzing antibody levels and binding kinetics in patient blood
  • Extracellular vesicle (EV) characterization
  • Fast sandwich assays using gold nanoparticles
  • Potency / denaturation assays
  • DNA / RNA
    • Quantification
    • Hybridization
    • And more
  • Allergen testing in food
    • Peanut
    • Progesterone in dairy milk
  • A wide range of interaction analyses, including potency assays, enzymatic lysis, etc.

The FO-SPR probes can be coupled with a range of compoundsMake use of the flexibility provided by the generic carboxyl chemistry.

Challenge us to help you with your application!

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