FOx BIOSYSTEMS flexible applications icon

Fiber-optic surface plasmon resonance (FO-SPR) is a versatile technology that can be adapted for use in a wide variety of additional applications.

Our interchangeable probes are available with four surface chemistries, allowing you to select the most appropriate method for your bioassay.

Carboxyl
A generic surface chemistry that serves a wide range of applications
NTA
For immobilized His-tag proteins; convenient for nanobodies and recombinant proteins and ideal for display library screening; allows multiplexing
Streptavidin
For easy immobilization of biotin-labelled proteins, antibodies or peptides
Protein A
A generic surface for quantifying IgG; ideal for screening IgG libraries for binding potency

This combination of probes allows the quantification of proteins, small molecules, DNA or cells in microliter volumes, as well as a wide range of interaction analyses.

Furthermore, the fluidics-free setup also eliminates the clogging associated with microfluidics-based alternatives, thereby reducing sample processing steps.

See the publication list for more examples of what scientists are doing with our technology.

Some of the other exciting things scientists are using our technology for:

  • Biologics production
    • Nanobody- or antibody-antigen kinetic affinity
    • Cellular bioreactor development
    • In-line process control systems
    • Analyzing antibody levels and binding kinetics in patient blood
  • Extracellular vesicle (EV) characterization
  • Fast sandwich assays using gold nanoparticles
  • Potency / denaturation assays
  • DNA / RNA
    • Quantification
    • Hybridization
    • And more
  • Allergen testing in food
    • Peanut
    • Progesterone in dairy milk
  • A wide range of interaction analyses, including potency assays, enzymatic lysis, etc.

The FO-SPR probes can be coupled with a range of compoundsMake use of the flexibility provided by the generic carboxyl chemistry.

Challenge us to help you with your application!

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