Fiber-optic surface plasmon resonance (FO-SPR) is a versatile technology that can be adapted for use in a wide variety of additional applications.
The probe has a standard generic coupling chemistry that can be coupled with a range of compounds and used with or without labels. This allows the quantification of proteins, small molecules, DNA or cells in microliter volumes, as well as a wide range of interaction analyses.
Additional probe types are in development and will open up an even broader range of applications.
The fluidics-free setup also eliminates the clogging associated with microfluidics-based alternatives, thereby reducing sample processing steps.